Antifungal agents: An introduction, classification, mechanism, uses, with its effects.

Antifungal drugs (agents)

Fungus-in-The-laboratory
Fungus in the laboratory

Antifungal agents (drugs) are the drugs that selectively eliminate fungal pathogens through a host with the least toxicity to the host cells. These are the substances that inhibit the spread of fungi either by killing fungal cells or spores or preventing their growth. These are killed fungi or inhibits their growth. Those kill fungi are called fungicidal while those are only inhibiting their growth are called fungistatic.

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Treatment of Tuberculosis: An introduction, symptoms, medication, with its effects.

Treatment of Tuberculosis

Bacteria-of-tuberculosis

Tuberculosis (TB) is an infectious disease that generally affects the lungs, however, it can affect any organ in the body. TB can be developing by spread the bacteria droplets in the air. It can be fatal, but in many cases, it is preventable and treatable. TB is a potentially serious infectious disease that mainly affects your lungs directly. When a person may inhale Mycobacterium tuberculosis (M. tuberculosis) bacteria then after developing TB.

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Aminoglycosides: An introduction, classification, mechanism, structure, uses, with its effects.

Aminoglycoside

structure-of-aminoglycosides
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Aminoglycoside is mainly distributed into the extracellular fluid and penetrates into the CSF. These are not metabolized in the body. They are excreted unchanged in the urine.

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Tetracycline: An introduction, classification, mechanism, structure, uses with its effects.

Tetracycline

Structure-of-tetracycline

The meaning of tetracycline is that Tetra- four, cycl- hydrocarbon ring, and ine- derivation. These are chemically octahydronapthacene ring derivatives which are bacteriostatic and board spectrum antibiotics that kill certain infections that causing microorganisms and used to treat a wide variety of infections. It was firstly obtained from the fermentation of the streptomyces spp.

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Cephalosporin: An introduction, classification, mechanism, structure, uses, with its effect.

Cephalosporin
Structure-of-cephalosporin

A cephalosporin is a group of semisynthetic antibiotics obtained naturally from “cephalosporin C” that is obtained from a fungus Cephaosporium acremonium. It is the compound that first isolated from cultures of “Cephalosporium acremonium” from a sewer in Sardinia by Italian scientist “Giuseppe Brotzu” in 1948.

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β-Lactam antibiotics: An introduction, classification, mechanism, structure, with its effects.

Βeta lactam antibiotics

Structure-of-beta-lactam-antibiotics

Beta-lactam is a class of antibiotics that blocks the activity of beta-lactamase enzymes, also called beta-lactamase. It prevents the degradation of beta-lactamase antibiotics with its action. They tend to have little antibiotic activity on their own.

Beta-lactamases are an antibiotic agent that contains the beta-lactam ring of susceptible penicillin and cephalosporins for inactivating the antibiotic. Some antimicrobials e.g.- cefazolin and cloxacillin are naturally resistant to certain Beta-lactamases.

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Cotrimoxazole: An introduction, classification, mechanism, synthesis with its effect.

Cotrimoxazole

The combination of trimethoprim and sulfamethoxazole within a fixed-dose in the ratio of 5:1 is called cotrimoxazole. It is a drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms with their action. Trimethoprim is a diaminopyrimidine related to the antimalarial drugs pyrimethamine which selectively inhibits bacterial dihydrofolate reductase (DHFRase).

Structure-of-Trimethoprim-and-Sulfamethoxazole
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Antimicrobial agents: An introduction, classification, mechanism, with its adverse effects.

Anti-microbial agent

Antimicrobial is an agent that kills or stop the growth of microorganism.

Anti-Microbial-agent
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The antimicrobial agents are interfering with the growth of microbes within a host. Antimicrobial agents or drugs are having the greatest contribution in the 20th century to therapeutics. The arrival of antimicrobial agents changed the viewpoint of the physicians that the power drugs can use for diseases.

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